An interesting study was recently presented at the ApA conference: there is now limited testing available to determine which SSRI or SNRI antidepressant medication is more likely to work for you based upon your genetics.  The study was funded by the testing company, but is worth looking into for more information.  Hopefully this will prevent the “hit or miss” experimental approach of selecting antidepressants based upon side-effect profiles, and waiting 2-6 weeks to find out if the clinical guess was a good one or not.  The article is on Medscape (you might need to register for a free account to access it).